Effects of Electroacupuncture of Different Frequencies on the Release Profile of Endogenous Opioid Peptides in the Central Nerve System of Goats

To investigate the release profile of met-enkephalin, β-endorphin, and dynorphin-A in ruminants’ CNS, goats were stimulated by electroacupuncture of 0, 2, 40, 60, 80, or 100 Hz for 30 min. The pain threshold was measured using potassium iontophoresis. The peptide levels were determined with SABC imm...

Full description

Saved in:
Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-9
Main Authors: Xiong, Cheng, Wang, Qiong, Qiu, Zheng-Ying, Zhou, Min-Yan, Ding, Ming-Xing, Cheng, Li-Li
Format: Article
Language:English
Subjects:
Acupuncture
Amygdala
Analgesia
Analgesics
Brain research
Caprinae
Caudate nucleus
Central nervous system
Dorsal horn
Dorsal raphe nucleus
Dynorphin
Electroacupuncture
Endorphins
Enkephalin (methionine)
Enkephalins
Eph protein
Goats
Hypothalamus
Hypothalamus (ventromedial)
Iontophoresis
Medical research
Narcotics
Nucleus accumbens
Opioid peptides
Opioids
Pain
Pain perception
Parabrachial nucleus
Paraventricular nucleus
Peptides
Periaqueductal gray area
Physiology
Potassium
Raphe nuclei
Spinal cord
Substantia nigra
Supraoptic nucleus
Veterinary medicine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To investigate the release profile of met-enkephalin, β-endorphin, and dynorphin-A in ruminants’ CNS, goats were stimulated by electroacupuncture of 0, 2, 40, 60, 80, or 100 Hz for 30 min. The pain threshold was measured using potassium iontophoresis. The peptide levels were determined with SABC immunohistochemisty. The results showed that 60 Hz increased pain threshold by 91%; its increasing rate was higher (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2012/476457