Measurement of vitamin A, vitamin E, selenium, and L-lactate in dogs with and without osteoarthritis secondary to ruptured cranial cruciate ligament

This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cranial cruciate ligament rupture and OA. Concentrations of vitamin E were significantly higher in serum...

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Bibliographic Details
Published in:Canadian veterinary journal 2012-12, Vol.53 (12), p.1285-1288
Main Authors: de Oliveira El-Warrak, Alexander, Rouma, Mouhamed, Amoroso, Audrey, Boysen, Soren R, Chorfi, Younés
Format: Article
Language:English
Subjects:
Animals
Anterior Cruciate Ligament Injuries
Case-Control Studies
Dog Diseases - blood
Dog Diseases - metabolism
Dogs
Female
Lactates - blood
Male
Osteoarthritis - blood
Osteoarthritis - metabolism
Osteoarthritis - veterinary
Rupture, Spontaneous - blood
Rupture, Spontaneous - metabolism
Rupture, Spontaneous - veterinary
Scientific
Selenium - blood
Selenium - metabolism
Synovial Fluid - chemistry
Vitamin A - blood
Vitamin A - metabolism
Vitamin E - blood
Vitamin E - metabolism
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Summary:This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cranial cruciate ligament rupture and OA. Concentrations of vitamin E were significantly higher in serum than in synovial fluid in both OA (P = 0.006) and control (P = 0.0008) groups. Vitamin E concentration in synovial fluid was significantly higher in the OA group than in the control group (P = 0.009). Concentrations of Se were significantly higher in serum than in synovial fluid in both OA (P = 0.003) and control (P = 0.0006) groups. There were no significant differences in levels of Se, vitamin A, and L-lactate between the 2 groups. This is the first study to show an increased concentration of vitamin E in the synovial fluid of dogs with OA compared with dogs that did not have OA.
ISSN:0008-5286