Cholesterol and prostate cancer

Graphical abstract Highlights ► Hypercholesterolemia increases the risk of aggressive prostate cancer. ► Cholesterol-lowering statin drugs reduce the risk of aggressive prostate cancer. ► Hypercholesterolemia may elicit multiple mechanisms that affect prostate cancer. ► Hypercholesterolemia may be a...

Full description

Saved in:
Bibliographic Details
Published in:Current opinion in pharmacology 2012-12, Vol.12 (6), p.751-759
Main Authors: Pelton, Kristine, Freeman, Michael R, Solomon, Keith R
Format: Article
Language:English
Subjects:
Animals
Anticholesteremic Agents - therapeutic use
Cholesterol - metabolism
Disease Models, Animal
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - drug therapy
Internal Medicine
Male
Medical Education
Models, Biological
Prostatic Neoplasms - etiology
Prostatic Neoplasms - pathology
Prostatic Neoplasms - prevention & control
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73
cites cdi_FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73
container_end_page 759
container_issue 6
container_start_page 751
container_title Current opinion in pharmacology
container_volume 12
creator Pelton, Kristine
Freeman, Michael R
Solomon, Keith R
description Graphical abstract Highlights ► Hypercholesterolemia increases the risk of aggressive prostate cancer. ► Cholesterol-lowering statin drugs reduce the risk of aggressive prostate cancer. ► Hypercholesterolemia may elicit multiple mechanisms that affect prostate cancer. ► Hypercholesterolemia may be a risk factor for developing castration-resistance.
doi_str_mv 10.1016/j.coph.2012.07.006
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3515742</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1471489212001178</els_id><sourcerecordid>1223431925</sourcerecordid><originalsourceid>FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73</originalsourceid><addsrcrecordid>eNp9kU9v1DAQxS0EoqXwBTjAHrlsmLHjOJFQpWrFP6lSD4XzyLFnWS_ZeLGzlfrt62jbCjj0ZEt-73nm94R4i1AhYPNxW7m431QSUFZgKoDmmTjF2uCy7ox6_nBvO3kiXuW8BUCtlHkpTqRsZV0rOBXvV5s4cJ44xWFhR7_Yp5gnO_HC2dFxei1erO2Q-c39eSZ-fvn8Y_VteXn19fvq4nLpNMK0VKwMa-11gxLRdxagBid1h27dN62XrffKGWPbuldK9rwGa2zfgOt966xRZ-L8mLs_9Dv2jscp2YH2KexsuqVoA_37MoYN_Yo3pDRqU8sS8OE-IMU_h7IR7UJ2PAx25HjIhFKqWmEndZHKo9SVXXPi9eM3CDSTpS3NZGkmS2CokC2md38P-Gh5QFkEn44CLphuAifKLnBh6ENiN5GP4en88__sbghjcHb4zbect_GQxlIAIeXioeu527lalKVWNK26A-AFnpw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1223431925</pqid></control><display><type>article</type><title>Cholesterol and prostate cancer</title><source>ScienceDirect Freedom Collection</source><creator>Pelton, Kristine ; Freeman, Michael R ; Solomon, Keith R</creator><creatorcontrib>Pelton, Kristine ; Freeman, Michael R ; Solomon, Keith R</creatorcontrib><description>Graphical abstract Highlights ► Hypercholesterolemia increases the risk of aggressive prostate cancer. ► Cholesterol-lowering statin drugs reduce the risk of aggressive prostate cancer. ► Hypercholesterolemia may elicit multiple mechanisms that affect prostate cancer. ► Hypercholesterolemia may be a risk factor for developing castration-resistance.</description><identifier>ISSN: 1471-4892</identifier><identifier>EISSN: 1471-4973</identifier><identifier>DOI: 10.1016/j.coph.2012.07.006</identifier><identifier>PMID: 22824430</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Anticholesteremic Agents - therapeutic use ; Cholesterol - metabolism ; Disease Models, Animal ; Humans ; Hypercholesterolemia - complications ; Hypercholesterolemia - drug therapy ; Internal Medicine ; Male ; Medical Education ; Models, Biological ; Prostatic Neoplasms - etiology ; Prostatic Neoplasms - pathology ; Prostatic Neoplasms - prevention &amp; control ; Risk Factors</subject><ispartof>Current opinion in pharmacology, 2012-12, Vol.12 (6), p.751-759</ispartof><rights>Elsevier Ltd</rights><rights>2012 Elsevier Ltd</rights><rights>Copyright © 2012 Elsevier Ltd. All rights reserved.</rights><rights>2012 Elsevier Ltd. All rights reserved. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73</citedby><cites>FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22824430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pelton, Kristine</creatorcontrib><creatorcontrib>Freeman, Michael R</creatorcontrib><creatorcontrib>Solomon, Keith R</creatorcontrib><title>Cholesterol and prostate cancer</title><title>Current opinion in pharmacology</title><addtitle>Curr Opin Pharmacol</addtitle><description>Graphical abstract Highlights ► Hypercholesterolemia increases the risk of aggressive prostate cancer. ► Cholesterol-lowering statin drugs reduce the risk of aggressive prostate cancer. ► Hypercholesterolemia may elicit multiple mechanisms that affect prostate cancer. ► Hypercholesterolemia may be a risk factor for developing castration-resistance.</description><subject>Animals</subject><subject>Anticholesteremic Agents - therapeutic use</subject><subject>Cholesterol - metabolism</subject><subject>Disease Models, Animal</subject><subject>Humans</subject><subject>Hypercholesterolemia - complications</subject><subject>Hypercholesterolemia - drug therapy</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical Education</subject><subject>Models, Biological</subject><subject>Prostatic Neoplasms - etiology</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Prostatic Neoplasms - prevention &amp; control</subject><subject>Risk Factors</subject><issn>1471-4892</issn><issn>1471-4973</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kU9v1DAQxS0EoqXwBTjAHrlsmLHjOJFQpWrFP6lSD4XzyLFnWS_ZeLGzlfrt62jbCjj0ZEt-73nm94R4i1AhYPNxW7m431QSUFZgKoDmmTjF2uCy7ox6_nBvO3kiXuW8BUCtlHkpTqRsZV0rOBXvV5s4cJ44xWFhR7_Yp5gnO_HC2dFxei1erO2Q-c39eSZ-fvn8Y_VteXn19fvq4nLpNMK0VKwMa-11gxLRdxagBid1h27dN62XrffKGWPbuldK9rwGa2zfgOt966xRZ-L8mLs_9Dv2jscp2YH2KexsuqVoA_37MoYN_Yo3pDRqU8sS8OE-IMU_h7IR7UJ2PAx25HjIhFKqWmEndZHKo9SVXXPi9eM3CDSTpS3NZGkmS2CokC2md38P-Gh5QFkEn44CLphuAifKLnBh6ENiN5GP4en88__sbghjcHb4zbect_GQxlIAIeXioeu527lalKVWNK26A-AFnpw</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Pelton, Kristine</creator><creator>Freeman, Michael R</creator><creator>Solomon, Keith R</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20121201</creationdate><title>Cholesterol and prostate cancer</title><author>Pelton, Kristine ; Freeman, Michael R ; Solomon, Keith R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Anticholesteremic Agents - therapeutic use</topic><topic>Cholesterol - metabolism</topic><topic>Disease Models, Animal</topic><topic>Humans</topic><topic>Hypercholesterolemia - complications</topic><topic>Hypercholesterolemia - drug therapy</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical Education</topic><topic>Models, Biological</topic><topic>Prostatic Neoplasms - etiology</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Prostatic Neoplasms - prevention &amp; control</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pelton, Kristine</creatorcontrib><creatorcontrib>Freeman, Michael R</creatorcontrib><creatorcontrib>Solomon, Keith R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current opinion in pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pelton, Kristine</au><au>Freeman, Michael R</au><au>Solomon, Keith R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cholesterol and prostate cancer</atitle><jtitle>Current opinion in pharmacology</jtitle><addtitle>Curr Opin Pharmacol</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>12</volume><issue>6</issue><spage>751</spage><epage>759</epage><pages>751-759</pages><issn>1471-4892</issn><eissn>1471-4973</eissn><abstract>Graphical abstract Highlights ► Hypercholesterolemia increases the risk of aggressive prostate cancer. ► Cholesterol-lowering statin drugs reduce the risk of aggressive prostate cancer. ► Hypercholesterolemia may elicit multiple mechanisms that affect prostate cancer. ► Hypercholesterolemia may be a risk factor for developing castration-resistance.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>22824430</pmid><doi>10.1016/j.coph.2012.07.006</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1471-4892
ispartof Current opinion in pharmacology, 2012-12, Vol.12 (6), p.751-759
issn 1471-4892
1471-4973
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3515742
source ScienceDirect Freedom Collection
subjects Animals
Anticholesteremic Agents - therapeutic use
Cholesterol - metabolism
Disease Models, Animal
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - drug therapy
Internal Medicine
Male
Medical Education
Models, Biological
Prostatic Neoplasms - etiology
Prostatic Neoplasms - pathology
Prostatic Neoplasms - prevention & control
Risk Factors
title Cholesterol and prostate cancer
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T00%3A34%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cholesterol%20and%20prostate%20cancer&rft.jtitle=Current%20opinion%20in%20pharmacology&rft.au=Pelton,%20Kristine&rft.date=2012-12-01&rft.volume=12&rft.issue=6&rft.spage=751&rft.epage=759&rft.pages=751-759&rft.issn=1471-4892&rft.eissn=1471-4973&rft_id=info:doi/10.1016/j.coph.2012.07.006&rft_dat=%3Cproquest_pubme%3E1223431925%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c510t-3e37e55d561211d9a0040c2591cfb68d28dd3c77a84b332bef0a7ab60cbd8ca73%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1223431925&rft_id=info:pmid/22824430&rfr_iscdi=true