Ion mobility spectrometry for detection of skin volatiles

► Fast and direct method is proposed for monitoring of trace VOCs emitted by human skin. Volatile organic compounds (VOCs) released by humans through their skin were investigated in near real time using ion mobility spectrometry after gas chromatographic separation with a short multi-capillary colum...

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Bibliographic Details
Published in:Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2012-12, Vol.911 (1), p.84-92
Main Authors: Ruzsanyi, Veronika, Mochalski, Pawel, Schmid, Alex, Wiesenhofer, Helmut, Klieber, Martin, Hinterhuber, Hartmann, Amann, Anton
Format: Article
Language:English
Subjects:
acetates
Adult
Benzaldehyde
Female
gas chromatography
Gas Chromatography-Mass Spectrometry - methods
Gas chromatography–mass spectrometry (GC–MS)
Gases - analysis
Gases - chemistry
Human
Humans
Ion mobility
Ion mobility spectrometry (IMS)
Ionic mobility
Male
Multi-capillary column (MCC)
nitrogen
Organic compounds
Reproducibility of Results
Skin - chemistry
Skin - metabolism
Skin emissions
Spectrometry
Spectroscopy
Volatile organic compounds
Volatile organic compounds (VOC)
Volatile Organic Compounds - analysis
Volatile Organic Compounds - chemistry
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Summary:► Fast and direct method is proposed for monitoring of trace VOCs emitted by human skin. Volatile organic compounds (VOCs) released by humans through their skin were investigated in near real time using ion mobility spectrometry after gas chromatographic separation with a short multi-capillary column. VOCs typically found in a small nitrogen flow covering the skin are 3-methyl-2-butenal, 6-methylhept-5-en-2-one, sec-butyl acetate, benzaldehyde, octanal, 2-ethylhexanol, nonanal and decanal at volume fractions in the low part per billion-(ppb) range. The technique presented here may contribute to elucidating some physiological processes occurring in the human skin.
ISSN:1570-0232
1873-376X
DOI:10.1016/j.jchromb.2012.10.028