Lamotrigine induced DRESS syndrome

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and life-threatening delayed drug hypersensitivity reaction characterized by skin eruption, fever, lymphadenopathies, and visceral involvement. Here, we are presenting a 12 year old boy, who developed rare but life threaten...

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Bibliographic Details
Published in:Indian journal of pharmacology 2012-11, Vol.44 (6), p.798-800
Main Authors: Naveen, Kikkeri Narayanasetty, Ravindra, Mysore Satyanarayana, Pai, Varadraj V, Rai, Vijetha, Athanikar, Sharatchandra B, Girish, Meravanige
Format: Article
Language:English
Subjects:
Allergic reaction
Allergy
Anticonvulsants - adverse effects
Child
Development and progression
Drug Hypersensitivity - etiology
Drug metabolism
Drug Watch
Eosinophilia - chemically induced
Health aspects
Humans
Hypersensitivity, Delayed - chemically induced
Inflammatory diseases
Lamotrigine
Male
Medical treatment
Pharmaceutical chemistry
Pharmacology
Physiological aspects
Side effects
Syndrome
Triazines - adverse effects
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Summary:Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and life-threatening delayed drug hypersensitivity reaction characterized by skin eruption, fever, lymphadenopathies, and visceral involvement. Here, we are presenting a 12 year old boy, who developed rare but life threatening DRESS syndrome due to Lamotrigine. Early detection and treatment led to his rapid recovery. This case is presented to highlight the importance of early detection of rare fatal syndrome.
ISSN:0253-7613
1998-3751
DOI:10.4103/0253-7613.103305