Jugular thrombophlebitis in horses: a review of fibrinolysis, thrombus formation, and clinical management

Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution...

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Bibliographic Details
Published in:Canadian veterinary journal 2013-01, Vol.54 (1), p.65-71
Main Authors: Dias, Deborah Penteado Martins, de Lacerda Neto, José Corrêa
Format: Article
Language:English
Subjects:
Animals
Blood Coagulation - physiology
Fibrinolysis - physiology
Fibrinolytic Agents - therapeutic use
Hemostasis
Horse Diseases - drug therapy
Horse Diseases - etiology
Horses
Jugular Veins
Risk Factors
Scientific
Thrombolytic Therapy
Thrombophlebitis - drug therapy
Thrombophlebitis - etiology
Thrombophlebitis - veterinary
Thrombosis - drug therapy
Thrombosis - etiology
Thrombosis - veterinary
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Summary:Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution and recanalization of the injured vessels. There are similarities between human and horse coagulation and fibrinolytic processes. This review examines the fibrinolytic system, thrombus formation, and the clinical management of jugular thrombophlebitis, including thrombolytic therapy. There is evidence that early regional thrombolytic therapy for jugular thrombophlebitis in horses may be effective to achieve sustained recanalization.
ISSN:0008-5286