Comparison of Mastoscopic and Conventional Axillary Lymph Node Dissection in Breast Cancer: Long-term Results From a Randomized, Multicenter Trial

Abstract Objective To compare the long-term results of mastoscopic axillary lymph node dissection (MALND) and conventional axillary lymph node dissection (CALND). Patients and Methods From January 1, 2003, through December 31, 2005, a group of 1027 consecutive patients with operable breast cancer we...

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Bibliographic Details
Published in:Mayo Clinic proceedings 2012-12, Vol.87 (12), p.1153-1161
Main Authors: Luo, Chengyu, PhD, MD, Guo, Wenbin, PhD, MD, Yang, Jie, Sun, Qiuru, BS, Wei, Wei, MD, Wu, Suhua, BS, Fang, Shubing, MS, Zeng, Qingliang, MD, Zhao, Zhensheng, MD, Meng, Fanjie, PhD, MD, Huang, Xuandong, MS, Zhang, Xianlan, MS, Li, Ruihua, MS, Ma, Xiufeng, MS, Luo, Chaoying, BS, Yang, Yun, MD
Format: Article
Language:English
Subjects:
Analysis
Axilla
Biological and medical sciences
Blood Loss, Surgical
Breast cancer
Breast Neoplasms - mortality
Breast Neoplasms - pathology
Carcinoma, Ductal, Breast - mortality
Carcinoma, Ductal, Breast - pathology
Carcinoma, Lobular - mortality
Carcinoma, Lobular - pathology
Disease-Free Survival
Edema - epidemiology
Esthetics
Female
General aspects
Gynecology. Andrology. Obstetrics
Humans
Hypesthesia - epidemiology
Internal Medicine
Lymph Node Excision - methods
Male
Mammary gland diseases
Medical sciences
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local
Original
Pain, Postoperative - epidemiology
Paresthesia - epidemiology
Survival Rate
Tumors
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Summary:Abstract Objective To compare the long-term results of mastoscopic axillary lymph node dissection (MALND) and conventional axillary lymph node dissection (CALND). Patients and Methods From January 1, 2003, through December 31, 2005, a group of 1027 consecutive patients with operable breast cancer were randomly assigned to 1 of 2 study groups: MALND and CALND. The median follow-up was 63 months. The primary end points of the study were operative outcomes, complication reduction, function conservation, and cosmetics. The secondary end points were disease-free and overall survival. Results The mean operative blood loss in the MALND group was less than in the CALND group ( P
ISSN:0025-6196
1942-5546
DOI:10.1016/j.mayocp.2012.07.022