Traveling waves in actin dynamics and cell motility

Highlights ► A growing number of studies report observations of self-organized actin waves. ► A majority (not all) of actin waves occur in excitable cytoskeleton. ► Mechanochemical feedbacks cause wave triggering, termination and spatial coupling. ► Actin waves can help cell movement in crowded spac...

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Bibliographic Details
Published in:Current opinion in cell biology 2013-02, Vol.25 (1), p.107-115
Main Authors: Allard, Jun, Mogilner, Alex
Format: Article
Language:English
Subjects:
Actins - metabolism
Cell Movement
Cytoplasm - metabolism
Humans
Internal Medicine
Movement
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Summary:Highlights ► A growing number of studies report observations of self-organized actin waves. ► A majority (not all) of actin waves occur in excitable cytoskeleton. ► Mechanochemical feedbacks cause wave triggering, termination and spatial coupling. ► Actin waves can help cell movement in crowded space or when protrusion is limited.
ISSN:0955-0674
1879-0410
DOI:10.1016/j.ceb.2012.08.012