Perspectives on the interface of drug delivery and tissue engineering

Controlled drug delivery of bioactive molecules continues to be an essential component of engineering strategies for tissue defect repair. This article surveys the current challenges associated with trying to regenerate complex tissues utilizing drug delivery and gives perspectives on the developmen...

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Bibliographic Details
Published in:Advanced drug delivery reviews 2013-01, Vol.65 (1), p.89-92
Main Authors: Ekenseair, Adam K., Kasper, F. Kurtis, Mikos, Antonios G.
Format: Article
Language:English
Subjects:
Biological Products - administration & dosage
Biological Products - chemistry
Drug Delivery Systems - methods
Extracellular matrix
Humans
Scaffolds
Spatiotemporal control
Tissue Engineering - methods
Tissue regeneration
Translational medicine
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Summary:Controlled drug delivery of bioactive molecules continues to be an essential component of engineering strategies for tissue defect repair. This article surveys the current challenges associated with trying to regenerate complex tissues utilizing drug delivery and gives perspectives on the development of translational tissue engineering therapies which promote spatiotemporal cell-signaling cascades to maximize the rate and quality of repair. [Display omitted]
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2012.08.017