Isolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China

Two swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is classical SI virus of recent years, which is of the main SI virus in China. Howere, A/swine/G...

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Published in:Indian Journal of Virology 2011-06, Vol.22 (1), p.66-71
Main Authors: Kong, Wei-li, Huang, Yu-mao, Cao, Nan, Qi, Hai-tao, Huang, Liang-zong, Zhao, Meng-meng, Guan, Shang-song, Wang, Wen-hua, Zhao, Fu-rong, Qi, Wen-bao, Jiao, Pei-rong, Zhang, Gui-hong
Format: Article
Language:English
Subjects:
Animal models
Antigens
Avian flu
Binding sites
Biochemistry
Biomedical and Life Sciences
Cell Biology
Epidemics
Genes
Hogs
Influenza
Life Sciences
Microbiology
Pandemics
Pathogenicity
Phylogenetics
Phylogeny
Protein Structure
Respiratory diseases
Short Communication
Swine flu
Swine influenza
Viruses
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Summary:Two swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is classical SI virus of recent years, which is of the main SI virus in China. Howere, A/swine/Guangdong/L3/09 was closet to A/swine/Iowa/1931, which was the first isolated SI virus and had demonstrated significant pathogenicity in animal models. The results of phylogenetic analysis of A/swine/Guangdong/L3/09 showed a close relationship with the 1918 pandemic virus. The results suggested that the previous SI virus appeared again. Whether, it brought a new pandemic to pigs deserves more attention.
ISSN:0970-2822
2347-3584
0974-0120
2347-3517
DOI:10.1007/s13337-011-0035-2