Cognitive dysfunction in elderly females with depressive symptoms

A depressive state is a common symptom in the elderly and often accompanies cognitive impairment. The coexistence of depressive symptoms and cognitive impairment is a serious problem, as it increases adverse outcomes for health, functional status, and mortality. It would thus be of great value to cl...

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Bibliographic Details
Published in:Medical science monitor 2012-12, Vol.18 (12), p.CR706-CR711
Main Authors: Tanaka, Masaaki, Ishii, Akira, Yamano, Emi, Ogikubo, Hiroki, Okazaki, Masatsugu, Kamimura, Kazuro, Konishi, Yasuharu, Emoto, Shigeru, Watanabe, Yasuyoshi
Format: Article
Language:English
Subjects:
Aged
Clinical Research
Cognition Disorders - complications
Cognition Disorders - physiopathology
Depression - complications
Depression - epidemiology
Depression - physiopathology
Female
Humans
Japan - epidemiology
Logistic Models
Prevalence
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Summary:A depressive state is a common symptom in the elderly and often accompanies cognitive impairment. The coexistence of depressive symptoms and cognitive impairment is a serious problem, as it increases adverse outcomes for health, functional status, and mortality. It would thus be of great value to clarify the cognitive dysfunction associated with depressive symptoms. We aimed to identify the cognitive dysfunction, in particular, impairment of the response inhibition component of executive function, associated with depressive symptoms in elderly females using the Simple Color Reaction Test and Modified Stroop Color-Word Test. The study group consisted of 35 elderly women. They performed cognitive function task trials for 9 min. Univariate logistic regression analyses were performed to identify factors associated with the prevalence of the depressive state. Longer reaction time and lower correction rate of response inhibition trials were related to the prevalence of the depressive symptoms. Impaired function of response inhibition may be a specific feature of the depressive state. Our findings may help clarify the neural mechanisms underlying the depressive state of elderly females.
ISSN:1234-1010
1643-3750
DOI:10.12659/MSM.883596