Use of panitumumab in the treatment of acinar cell carcinoma of the pancreas: A case report

Two cases of stage IV acinar carcinoma of the pancreas are presented. The two patients were treated with several lines of chemotherapies active against colon cancer. At last-line, both patients received panitumumab monotherapy. We describe the tumour response to the different therapies. Our findings...

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Bibliographic Details
Published in:Oncology letters 2013-03, Vol.5 (3), p.969-971
Main Authors: MORALES, MANUEL, CABRERA, MIGUEL ÁNGEL, MAESO, MARIA DEL CARMEN, FERRER-LÓPEZ, NOEMÍ
Format: Article
Language:English
Subjects:
Abdomen
acinar cell carcinoma of pancreas
Cancer therapies
Case reports
Chemotherapy
Colorectal cancer
Diabetes
Edema
Immunotherapy
KRAS
Medical prognosis
Metastasis
Monoclonal antibodies
Multivariate analysis
Mutation
NMR
Nuclear magnetic resonance
Pancreas
Pancreatic cancer
panitumumab
Patients
Spleen
Targeted cancer therapy
Tumors
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Summary:Two cases of stage IV acinar carcinoma of the pancreas are presented. The two patients were treated with several lines of chemotherapies active against colon cancer. At last-line, both patients received panitumumab monotherapy. We describe the tumour response to the different therapies. Our findings demonstrate that panitumumab produces objective responses when used as third-line treatment in the therapy of patients with acinar cell carcinoma of the pancreas. Thus, we propose the consideration of the use of panitumumab in early lines of treatment.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2012.1083