The Role of Canonical and Noncanonical Pre-mRNA Splicing in Plant Stress Responses

Plants are sessile organisms capable of adapting to various environmental constraints, such as high or low temperatures, drought, soil salinity, or pathogen attack. To survive the unfavorable conditions, plants actively employ pre-mRNA splicing as a mechanism to regulate expression of stress-respons...

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Bibliographic Details
Published in:BioMed research international 2013-01, Vol.2013 (2013), p.1-14
Main Authors: Dubrovina, A. S., Zhuravlev, Yu. N., Kiselev, K. V.
Format: Article
Language:English
Subjects:
Alternative Splicing
Arabidopsis - genetics
Codon, Nonsense
Databases, Genetic
Exons
Gene Expression Regulation, Plant
Genes, Plant
Genetic aspects
Messenger RNA
Physiological aspects
Plant Proteins - metabolism
Plants
Plants - genetics
Proteomics
Review
RNA Precursors - genetics
RNA, Messenger - metabolism
Spliceosomes - metabolism
Stress (Physiology)
Stress, Physiological
Trans-Splicing
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Summary:Plants are sessile organisms capable of adapting to various environmental constraints, such as high or low temperatures, drought, soil salinity, or pathogen attack. To survive the unfavorable conditions, plants actively employ pre-mRNA splicing as a mechanism to regulate expression of stress-responsive genes and reprogram intracellular regulatory networks. There is a growing evidence that various stresses strongly affect the frequency and diversity of alternative splicing events in the stress-responsive genes and lead to an increased accumulation of mRNAs containing premature stop codons, which in turn have an impact on plant stress response. A number of studies revealed that some mRNAs involved in plant stress response are spliced counter to the traditional conception of alternative splicing. Such noncanonical mRNA splicing events include trans-splicing, intraexonic deletions, or variations affecting multiple exons and often require short direct repeats to occur. The noncanonical alternative splicing, along with common splicing events, targets the spliced transcripts to degradation through nonsense-mediated mRNA decay or leads to translation of truncated proteins. Investigation of the diversity, biological consequences, and mechanisms of the canonical and noncanonical alternative splicing events will help one to identify those transcripts which are promising for using in genetic engineering and selection of stress-tolerant plants.
ISSN:2314-6133
2314-6141
DOI:10.1155/2013/264314