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Effects of Gut Microbes on Nutrient Absorption and Energy Regulation

Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet. The composition of the gut microbiota has been shown to differ between lean and obe...

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Published in:	Nutrition in clinical practice 2012-04, Vol.27 (2), p.201-214
Main Authors:	Krajmalnik-Brown, Rosa, Ilhan, Zehra-Esra, Kang, Dae-Wook, DiBaise, John K.
Format:	Article
Language:	English
Subjects:	absorption Animals Bacteria Dietary Fats - metabolism Energy Metabolism Gastrointestinal Tract - metabolism Gastrointestinal Tract - microbiology Humans Inflammation Intestinal Absorption Life Sciences Lipopolysaccharides malnutrition Malnutrition - metabolism Malnutrition - microbiology Metagenome microbiome obesity Obesity - metabolism Obesity - microbiology
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creator	Krajmalnik-Brown, Rosa Ilhan, Zehra-Esra Kang, Dae-Wook DiBaise, John K.
description	Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet. The composition of the gut microbiota has been shown to differ between lean and obese humans and mice; however, the specific roles that individual gut microbes play in energy harvest remain uncertain. The gut microbiota may also influence the development of conditions characterized by chronic low-level inflammation, such as obesity, through systemic exposure to bacterial lipopolysaccharide derived from the gut microbiota. In this review, the role of the gut microbiota in energy harvest and fat storage is explored, as well as differences in the microbiota in obesity and undernutrition.
doi_str_mv	10.1177/0884533611436116
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subjects	absorption Animals Bacteria Dietary Fats - metabolism Energy Metabolism Gastrointestinal Tract - metabolism Gastrointestinal Tract - microbiology Humans Inflammation Intestinal Absorption Life Sciences Lipopolysaccharides malnutrition Malnutrition - metabolism Malnutrition - microbiology Metagenome microbiome obesity Obesity - metabolism Obesity - microbiology
title	Effects of Gut Microbes on Nutrient Absorption and Energy Regulation
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