Phosphate induced crystal acute kidney injury - an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature

Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition - crystal nephropathy - and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patien...

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Bibliographic Details
Published in:International journal of nephrology and renovascular disease 2013-01, Vol.6, p.61-64
Main Authors: Lochy, S, Jacobs, R, Honoré, P M, De Waele, E, Joannes-Boyau, O, De Regt, J, Van Gorp, V, Spapen, H D
Format: Article
Language:English
Subjects:
Care and treatment
Case Report
Case reports
Case studies
Chronic kidney failure
Diagnosis
Dialysis
Health aspects
Kidney diseases
Kidneys
Phosphates
Risk factors
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Summary:Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition - crystal nephropathy - and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administration of a combination of oral and rectal sodium phosphate for treatment of postoperative constipation. A timely renal replacement therapy procedure may reverse the process of crystallization and the irreversible slope towards chronic dialysis.
ISSN:1178-7058
1178-7058
DOI:10.2147/IJNRD.S41428