The efficacy of 8% Arginine-CaCO₃ applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study

• Published in: Medicina oral, patología oral y cirugía bucal patología oral y cirugía bucal, 2013-03, Vol.18 (2), p.e298-e305
• Main Authors: Uraz, Ahu, Erol-Şimşek, Özge, Pehlivan, Selcen, Suludere, Zekiye, Bal, Belgin
• Format: Article
• Language: English
• Subjects: Adult; Arginine - administration & dosage; Calcium Carbonate - administration & dosage; Dentin Sensitivity - drug therapy; Dentin Sensitivity - pathology; Dentistry; Double-Blind Method; Drug Combinations; Female; Humans; Microscopy, Electron, Scanning; Periodontal Diseases - therapy; Periodontology
• ISSN: 1698-6946; 1698-4447; 1698-6946
• DOI: 10.4317/medoral.17990

Periodontal therapy is one of the etiological factors of dentine hypersensitivity (DH). This study aimed to evaluate the efficacy of %8Arginine-CaCO₃ on DH that affects patients after periodontal treatment. Seventy-one teeth from the volunteers (n=36) with history of DH caused by periodontal therapy were included in this study, and randomly divided into two groups: group-1, who received 8%Arginine-CaCO₃ and group-2, who received 1.23%NaF-gel. The clinical indices were recorded at first visit.DH was evaluated by using tactile, air-blast, and thermal stimuli. The subject's response was recorded at baseline, immediately (Day-0) and one month after the application. The results were statistically analyzed, and it was found that 8% Arginine-CaCO₃ treatment was more effective than 1.23% NaF-gel at time intervals. Sensitivity score differences between the groups were statistically significant at Day-28. The 8% Arginine-CaCO₃ group exhibited statistically significant reduction in DH on three stimuli at baseline to Day-28. It was concluded that 8% Arginine-CaCO₃ is more effective than 1.23% NaF-gel in reduction of patients' pain.