Two-photon luminescence properties of gold nanorods

Gold nanorods can be internalized by macrophages (an important early cellular marker in atherosclerosis and cancer) and used as an imaging contrast agent for macrophage targeting. Objective of this study is to compare two-photon luminescence (TPL) properties of four aspect ratios of gold nanorods wi...

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Bibliographic Details
Published in:Biomedical optics express 2013-04, Vol.4 (4), p.584-595
Main Authors: Wang, Tianyi, Halaney, David, Ho, Derek, Feldman, Marc D, Milner, Thomas E
Format: Article
Language:English
Subjects:
Nanotechnology and Plasmonics
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Summary:Gold nanorods can be internalized by macrophages (an important early cellular marker in atherosclerosis and cancer) and used as an imaging contrast agent for macrophage targeting. Objective of this study is to compare two-photon luminescence (TPL) properties of four aspect ratios of gold nanorods with surface plasmon resonance at 700, 756, 844 and 1060 nm respectively. TPL from single nanorods and Rhodamine 6G particles was measured using a laser-scanning TPL microscope. Nanorod TPL emission spectrum was recorded by a spectrometer. Quadratic dependence of luminescence intensity on excitation power (confirming a TPL process) was observed below a threshold (e.g.,
ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.4.000584