Measurement of cartilage thickness in the human knee-joint by magnetic resonance imaging using a three-dimensional gradient-echo sequence

We studied human specimens and compared data on cartilage thickness measurements with magnetic resonance imaging by using an image analysing system with corresponding histological sections in the middle of each sector. The findings are based on 768 measurements in 26 knee joints. Overall, there was...

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Bibliographic Details
Published in:International orthopaedics 1999, Vol.23 (5), p.264-267
Main Authors: KLADNY, B, MARTUS, P, SCHIWY-BOCHAT, K.-H, WESELOH, G, SWOBODA, B
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Cartilage, Articular - pathology
Humans
Investigative techniques, diagnostic techniques (general aspects)
Knee Joint - pathology
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Original Paper
Osteoarthritis, Knee - pathology
Osteoarticular system. Muscles
Radiodiagnosis. Nmr imagery. Nmr spectrometry
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Summary:We studied human specimens and compared data on cartilage thickness measurements with magnetic resonance imaging by using an image analysing system with corresponding histological sections in the middle of each sector. The findings are based on 768 measurements in 26 knee joints. Overall, there was very good magnetic resonance/anatomic correlation (r=0.88). The poorest correlation was in the sectors of the femur (r=0.69). The correlation seemed not to be dependent on the grade of osteoarthritic cartilage lesions. Despite good correlation rates, the mean magnetic resonance/anatomic difference (absolute values) was 0.41 mm (standard deviation (SD) 0.34 mm) or 18.08% (SD 18.9%). Imaging techniques need to be improved if the assessment of cartilage thickness by this means is to be of clinical relevance.
ISSN:0341-2695
1432-5195
DOI:10.1007/s002640050367