Extracorporeally irradiated autografts in pelvic reconstruction after malignant tumour resection

We treated 15 patients suffering from an extracompartmental malignant pelvic tumour by resecting the affected part of the bone, irradiating it extracorporeally with 300 Gy, and reimplanting it after having removed the bulk of the lesion. Adjuvant therapies were used according to the type and extensi...

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Bibliographic Details
Published in:International orthopaedics 2002, Vol.26 (3), p.174-178
Main Authors: SYS, Gwen, UYTTENDAELE, Dirk, POFFYN, Bart, VERDONK, Rene, VERSTRAETE, Koenraad Luc
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Bone Neoplasms - radiotherapy
Bone Neoplasms - surgery
Bone Transplantation
Child
Chondrosarcoma - radiotherapy
Chondrosarcoma - surgery
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Male
Medical sciences
Middle Aged
Original Paper
Orthopedic surgery
Pelvic Bones - radiation effects
Pelvic Bones - surgery
Radiotherapy - methods
Replantation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Transplantation, Autologous
Treatment Outcome
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Summary:We treated 15 patients suffering from an extracompartmental malignant pelvic tumour by resecting the affected part of the bone, irradiating it extracorporeally with 300 Gy, and reimplanting it after having removed the bulk of the lesion. Adjuvant therapies were used according to the type and extension of the tumour. Follow-up was an average of 4 years 6 months. Complications were seen in 13 patients. Most mechanical complications were related to the use of hip arthroplasties. Internal fixation of the graft failed in one case only, infection was seen in three cases, and seven patients died after local recurrence. Functional scores were fair. Although many complications were seen, this method remains our treatment of choice.
ISSN:0341-2695
1432-5195
DOI:10.1007/s00264-002-0352-6