Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains

Objective:To investigate the in vitro antimicrobial activities of the leaf extract in different solvents viz.,methanol,ethanol and water extracts of the selected plant Ricinus communis.Methods:Ager well diffusion method and agar tube dilution method were carried out to perform the antibacterial and...

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Bibliographic Details
Published in:Asian Pacific journal of tropical biomedicine 2012-12, Vol.2 (12), p.944-947
Main Authors: Naz, Rabia, Bano, Asghari
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antibacterial
Antifungal
Antifungal Agents - pharmacology
Aspergillus - drug effects
Aspergillus flavus
Aspergillus fumigatus
Bacillus subtilis
communis
Ethanol
Gram-Negative Bacteria - drug effects
Gram-Positive Bacteria - drug effects
Humans
inhibition
Klebsiella pneumoniae
Methanol
Methanol - chemistry
Microbial Sensitivity Tests
Original
percentage
Plant Extracts - pharmacology
Plant Leaves - chemistry
Pseudomonas aeruginosa
Relative
Relative percentage inhibition
Ricinus
Ricinus - chemistry
Ricinus communis
Solvents - chemistry
Staphylococcus aureus
Water - chemistry
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Summary:Objective:To investigate the in vitro antimicrobial activities of the leaf extract in different solvents viz.,methanol,ethanol and water extracts of the selected plant Ricinus communis.Methods:Ager well diffusion method and agar tube dilution method were carried out to perform the antibacterial and antifungal activity of methanol,ethanol and aqueous extracts.Results:Metbanol leaf extracts were found to be more active against Gram positive bacteria(Bacillus subtilis:ATCC 6059 and Staphylococcus aureus:ATCC 6538)as well as Gram negative bacteria(Pseudomonas aeruginosa:ATCC 7221 and Klebsiella pneumoniae)than ethanol and aqueous leaf extracts.Antifungal activity of methanol and aqueous leaf extracts were also carded out against selected fungal strains as Aspergillus fumigatus and Aspergillus flavus.Methanolic as well as aqueous leaf extracts of Ricinus communis were effective in inhibiting the fungal growth.Conclusions:The efficient antibacterial and antifungai activity of Ricinus communis from the present investigation revealed that the methanol leaf extracts of the selected plant have significant potential to inhibit the growth of pathogenic bacterial and fungal strains than ethanol and aqueous leaf extracts.
ISSN:2221-1691
2588-9222
DOI:10.1016/S2221-1691(13)60004-0