Amidine Dications: Isolation and [Fe]-Hydrogenase-Related Hydrogenation

This commmunication demonstrates the preparation, isolation, and full characterization of superelectrophilic salts based on amidine dications in organic solvent, as their triflate salts. These dications are highly activated toward regiospecific reaction with hydrogen gas under mild conditions in the...

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Published in:Journal of the American Chemical Society 2009-07, Vol.131 (26), p.9174-9175
Main Authors: Corr, Michael J, Gibson, Kirsty F, Kennedy, Alan R, Murphy, John A
Format: Article
Language:English
Subjects:
Alkylation
Amidines - chemical synthesis
Amidines - chemistry
Bacteria - chemistry
Bacterial Proteins - chemistry
Biomimetics
Catalysis
Cations - chemical synthesis
Cations - chemistry
Communication
Crystallography, X-Ray
Hydrogen - chemistry
Hydrogenase - chemistry
Hydrogenation
Iron-Sulfur Proteins - chemistry
Molecular Structure
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cited_by cdi_FETCH-LOGICAL-a469t-d2c2e47183bf9c225efc8c7d547b6d454081875012bb136f369a80942d060bf43
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container_end_page 9175
container_issue 26
container_start_page 9174
container_title Journal of the American Chemical Society
container_volume 131
creator Corr, Michael J
Gibson, Kirsty F
Kennedy, Alan R
Murphy, John A
description This commmunication demonstrates the preparation, isolation, and full characterization of superelectrophilic salts based on amidine dications in organic solvent, as their triflate salts. These dications are highly activated toward regiospecific reaction with hydrogen gas under mild conditions in the presence of a metal catalyst (Pd/C), mimicking the behavior of the natural substrate, N 5,N 10-methenyltetrahydromethanopterin, in the iron−sulfur cluster-free [Fe]-hydrogenase.
doi_str_mv 10.1021/ja9035847
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Alkylation
Amidines - chemical synthesis
Amidines - chemistry
Bacteria - chemistry
Bacterial Proteins - chemistry
Biomimetics
Catalysis
Cations - chemical synthesis
Cations - chemistry
Communication
Crystallography, X-Ray
Hydrogen - chemistry
Hydrogenase - chemistry
Hydrogenation
Iron-Sulfur Proteins - chemistry
Molecular Structure
title Amidine Dications: Isolation and [Fe]-Hydrogenase-Related Hydrogenation
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