Vitamin C Deficiency in an Anticoagulated Patient

ABSTRACT A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C. Pat...

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Bibliographic Details
Published in:Journal of general internal medicine : JGIM 2013-06, Vol.28 (6), p.852-854
Main Authors: Yousef, George M., Goebel, Lynne J.
Format: Article
Language:English
Subjects:
Anticoagulants - adverse effects
Ascorbic Acid - therapeutic use
Ascorbic Acid Deficiency - chemically induced
Ascorbic Acid Deficiency - diagnosis
Ascorbic Acid Deficiency - drug therapy
Biological and medical sciences
Clinical Practice: Clinical Vignettes
Coagulation
Drug Eruptions - diagnosis
Drug Eruptions - etiology
Drug therapy
Female
General aspects
Humans
Internal Medicine
Leg Dermatoses - chemically induced
Leg Dermatoses - diagnosis
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Middle Aged
Other nutritional diseases (malnutrition, nutritional and vitamin deficiencies...)
Skin Diseases, Vascular - chemically induced
Skin Diseases, Vascular - diagnosis
Vitamin C
Warfarin - adverse effects
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Summary:ABSTRACT A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C. Patients on a vitamin K limited diet may also be limiting their intake of vitamin C. Physicians should be aware of this possible correlation, and consider checking vitamin C levels in patients with a perifollicular hemorrhagic rash or other signs of vitamin C deficiency while on warfarin.
ISSN:0884-8734
1525-1497
DOI:10.1007/s11606-012-2282-3