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Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders
A Structured Observational Analog Procedure (SOAP), an analogue measure of parent-child interactions, was used to assess treatment outcome in children with Autism Spectrum Disorder and serious behavior problems. It served as a secondary outcome measure in a 24-week, randomized trial of risperidone (...
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Published in: | Journal of developmental and physical disabilities 2013-06, Vol.25 (3), p.355-371 |
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container_title | Journal of developmental and physical disabilities |
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creator | Handen, Benjamin L. Johnson, Cynthia R. Butter, Eric M. Lecavalier, Luc Scahill, Lawrence Aman, Michael G. McDougle, Christopher J. Arnold, L. Eugene Swiezy, Naomi B. Sukhodolsky, Denis G. Mulick, James A. White, Susan W. Bearss, Karen Hollway, Jill A. Stigler, Kimberly A. Dziura, James Yu, Sunkyung Sacco, Kelley Vitiello, Benedetto |
description | A Structured Observational Analog Procedure (SOAP), an analogue measure of parent-child interactions, was used to assess treatment outcome in children with Autism Spectrum Disorder and serious behavior problems. It served as a secondary outcome measure in a 24-week, randomized trial of risperidone (MED;
N
= 49) versus risperidone plus parent training (COMB;
n
= 75) (ages 4–13 years). At 24-weeks, there was 28 % reduction in child inappropriate behavior during a Demand Condition (
p
= .0002) and 12 % increase in compliance to parental requests (
p
= .004) for the two treatment conditions combined. Parents displayed 64 % greater use of positive reinforcement (
p
= .001) and fewer repeated requests for compliance (
p
|
doi_str_mv | 10.1007/s10882-012-9316-y |
format | article |
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N
= 49) versus risperidone plus parent training (COMB;
n
= 75) (ages 4–13 years). At 24-weeks, there was 28 % reduction in child inappropriate behavior during a Demand Condition (
p
= .0002) and 12 % increase in compliance to parental requests (
p
= .004) for the two treatment conditions combined. Parents displayed 64 % greater use of positive reinforcement (
p
= .001) and fewer repeated requests for compliance (
p
< .0001). In the analysis of covariance (ANCOVA), COMB parents used significantly more positive reinforcement (
p
= .01) and fewer restrictive statements (
p
< .05) than MED parents. The SOAP is sensitive to change in child and parent behavior as a function of risperidone alone and in combination with PMT and can serve as a valuable complement to parent and clinician-based measures.</description><identifier>ISSN: 1056-263X</identifier><identifier>EISSN: 1573-3580</identifier><identifier>DOI: 10.1007/s10882-012-9316-y</identifier><identifier>PMID: 23730123</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Analysis of covariance ; Antipsychotics ; Autism ; Autism Spectrum Disorders ; Autistic children ; Behavior problems ; Behavioral Science and Psychology ; Behaviour disordered children ; Child and School Psychology ; Compliance ; Developmental disorders ; Inappropriateness ; Original Article ; Outcome Measures ; Outcomes of Treatment ; Parent Child Relationship ; Parent-child relations ; Parenthood education ; Parents & parenting ; Pediatrics ; Pervasive developmental disorders ; Positive reinforcement ; Psychology ; Public Health ; Reinforcement ; Risperidone ; Statistical Analysis</subject><ispartof>Journal of developmental and physical disabilities, 2013-06, Vol.25 (3), p.355-371</ispartof><rights>Springer Science+Business Media New York 2012</rights><rights>Journal of Developmental and Physical Disabilities is a copyright of Springer, (2012). All Rights Reserved.</rights><rights>Springer Science+Business Media New York 2012 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-3c29726dad2324705b1c156e7c2150d53edb2e859e7b2012055533060dd54f1d3</citedby><cites>FETCH-LOGICAL-c503t-3c29726dad2324705b1c156e7c2150d53edb2e859e7b2012055533060dd54f1d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2259589305?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,12846,21378,21394,21395,27924,27925,30999,33611,33612,33877,33878,34530,34531,43733,43880,44115</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23730123$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Handen, Benjamin L.</creatorcontrib><creatorcontrib>Johnson, Cynthia R.</creatorcontrib><creatorcontrib>Butter, Eric M.</creatorcontrib><creatorcontrib>Lecavalier, Luc</creatorcontrib><creatorcontrib>Scahill, Lawrence</creatorcontrib><creatorcontrib>Aman, Michael G.</creatorcontrib><creatorcontrib>McDougle, Christopher J.</creatorcontrib><creatorcontrib>Arnold, L. Eugene</creatorcontrib><creatorcontrib>Swiezy, Naomi B.</creatorcontrib><creatorcontrib>Sukhodolsky, Denis G.</creatorcontrib><creatorcontrib>Mulick, James A.</creatorcontrib><creatorcontrib>White, Susan W.</creatorcontrib><creatorcontrib>Bearss, Karen</creatorcontrib><creatorcontrib>Hollway, Jill A.</creatorcontrib><creatorcontrib>Stigler, Kimberly A.</creatorcontrib><creatorcontrib>Dziura, James</creatorcontrib><creatorcontrib>Yu, Sunkyung</creatorcontrib><creatorcontrib>Sacco, Kelley</creatorcontrib><creatorcontrib>Vitiello, Benedetto</creatorcontrib><title>Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders</title><title>Journal of developmental and physical disabilities</title><addtitle>J Dev Phys Disabil</addtitle><addtitle>J Dev Phys Disabil</addtitle><description>A Structured Observational Analog Procedure (SOAP), an analogue measure of parent-child interactions, was used to assess treatment outcome in children with Autism Spectrum Disorder and serious behavior problems. It served as a secondary outcome measure in a 24-week, randomized trial of risperidone (MED;
N
= 49) versus risperidone plus parent training (COMB;
n
= 75) (ages 4–13 years). At 24-weeks, there was 28 % reduction in child inappropriate behavior during a Demand Condition (
p
= .0002) and 12 % increase in compliance to parental requests (
p
= .004) for the two treatment conditions combined. Parents displayed 64 % greater use of positive reinforcement (
p
= .001) and fewer repeated requests for compliance (
p
< .0001). In the analysis of covariance (ANCOVA), COMB parents used significantly more positive reinforcement (
p
= .01) and fewer restrictive statements (
p
< .05) than MED parents. The SOAP is sensitive to change in child and parent behavior as a function of risperidone alone and in combination with PMT and can serve as a valuable complement to parent and clinician-based measures.</description><subject>Analysis of covariance</subject><subject>Antipsychotics</subject><subject>Autism</subject><subject>Autism Spectrum Disorders</subject><subject>Autistic children</subject><subject>Behavior problems</subject><subject>Behavioral Science and Psychology</subject><subject>Behaviour disordered children</subject><subject>Child and School Psychology</subject><subject>Compliance</subject><subject>Developmental disorders</subject><subject>Inappropriateness</subject><subject>Original Article</subject><subject>Outcome Measures</subject><subject>Outcomes of Treatment</subject><subject>Parent Child Relationship</subject><subject>Parent-child relations</subject><subject>Parenthood education</subject><subject>Parents & parenting</subject><subject>Pediatrics</subject><subject>Pervasive developmental disorders</subject><subject>Positive reinforcement</subject><subject>Psychology</subject><subject>Public Health</subject><subject>Reinforcement</subject><subject>Risperidone</subject><subject>Statistical Analysis</subject><issn>1056-263X</issn><issn>1573-3580</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><sourceid>ALSLI</sourceid><sourceid>CJNVE</sourceid><sourceid>HEHIP</sourceid><sourceid>M0P</sourceid><sourceid>M2S</sourceid><recordid>eNqFkk1v1DAQhiNERUvhB3BBlrhwSeuPHSe5IKFdoEhFrVArcbOceHbXVdZe7GTR_gF-NxNtKR8S4mRr5pl3Zuy3KF4IfiY4r86z4HUtSy5k2Sihy_2j4kRApUoFNX9Mdw66lFp9OS6e5nzHOdeyaZ4Ux1JViqrUSfH9NiOLS2bZwifsBnbVZkw7O_gYbM8-oc1jQuYDETfJU4jgzz5vMXkXAzIbHLu2CcNAeeuDD6uJnq997yjKvvlhza4nyex3yBa4wz5uN8ST1sLnmBym_Kw4Wto-4_P787S4ff_uZn5RXl59-Dh_e1l2wNVQqk42ldTOOqnkrOLQik6AxqqTArgDha6VWEODVStpQQ4ASnHNnYPZUjh1Wrw56G7HdoOuozGS7c02-Y1NexOtN39mgl-bVdwZpTWABBJ4fS-Q4tcR82A2PnfY9zZgHLMRtdRQ0_NX_0e1lNA0lZgR-uov9C6OiT4gm4mBulF86i0OVJdizgmXD3MLbiZDmIMhDG1uJkOYPdW8_H3hh4qfDiBAHoBMqbDC9Kv1v1V_AJUlwdo</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Handen, Benjamin L.</creator><creator>Johnson, Cynthia R.</creator><creator>Butter, Eric M.</creator><creator>Lecavalier, Luc</creator><creator>Scahill, Lawrence</creator><creator>Aman, Michael G.</creator><creator>McDougle, Christopher J.</creator><creator>Arnold, L. Eugene</creator><creator>Swiezy, Naomi B.</creator><creator>Sukhodolsky, Denis G.</creator><creator>Mulick, James A.</creator><creator>White, Susan W.</creator><creator>Bearss, Karen</creator><creator>Hollway, Jill A.</creator><creator>Stigler, Kimberly A.</creator><creator>Dziura, James</creator><creator>Yu, Sunkyung</creator><creator>Sacco, Kelley</creator><creator>Vitiello, Benedetto</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0P</scope><scope>M0S</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7TS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130601</creationdate><title>Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders</title><author>Handen, Benjamin L. ; Johnson, Cynthia R. ; Butter, Eric M. ; Lecavalier, Luc ; Scahill, Lawrence ; Aman, Michael G. ; McDougle, Christopher J. ; Arnold, L. Eugene ; Swiezy, Naomi B. ; Sukhodolsky, Denis G. ; Mulick, James A. ; White, Susan W. ; Bearss, Karen ; Hollway, Jill A. ; Stigler, Kimberly A. ; Dziura, James ; Yu, Sunkyung ; Sacco, Kelley ; Vitiello, Benedetto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-3c29726dad2324705b1c156e7c2150d53edb2e859e7b2012055533060dd54f1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Analysis of covariance</topic><topic>Antipsychotics</topic><topic>Autism</topic><topic>Autism Spectrum Disorders</topic><topic>Autistic children</topic><topic>Behavior problems</topic><topic>Behavioral Science and Psychology</topic><topic>Behaviour disordered children</topic><topic>Child and School Psychology</topic><topic>Compliance</topic><topic>Developmental disorders</topic><topic>Inappropriateness</topic><topic>Original Article</topic><topic>Outcome Measures</topic><topic>Outcomes of Treatment</topic><topic>Parent Child Relationship</topic><topic>Parent-child relations</topic><topic>Parenthood education</topic><topic>Parents & parenting</topic><topic>Pediatrics</topic><topic>Pervasive developmental disorders</topic><topic>Positive reinforcement</topic><topic>Psychology</topic><topic>Public Health</topic><topic>Reinforcement</topic><topic>Risperidone</topic><topic>Statistical Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Handen, Benjamin L.</creatorcontrib><creatorcontrib>Johnson, Cynthia R.</creatorcontrib><creatorcontrib>Butter, Eric M.</creatorcontrib><creatorcontrib>Lecavalier, Luc</creatorcontrib><creatorcontrib>Scahill, Lawrence</creatorcontrib><creatorcontrib>Aman, Michael G.</creatorcontrib><creatorcontrib>McDougle, Christopher J.</creatorcontrib><creatorcontrib>Arnold, L. Eugene</creatorcontrib><creatorcontrib>Swiezy, Naomi B.</creatorcontrib><creatorcontrib>Sukhodolsky, Denis G.</creatorcontrib><creatorcontrib>Mulick, James A.</creatorcontrib><creatorcontrib>White, Susan W.</creatorcontrib><creatorcontrib>Bearss, Karen</creatorcontrib><creatorcontrib>Hollway, Jill A.</creatorcontrib><creatorcontrib>Stigler, Kimberly A.</creatorcontrib><creatorcontrib>Dziura, James</creatorcontrib><creatorcontrib>Yu, Sunkyung</creatorcontrib><creatorcontrib>Sacco, Kelley</creatorcontrib><creatorcontrib>Vitiello, Benedetto</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Social Science Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Education Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest sociology</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of developmental and physical disabilities</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Handen, Benjamin L.</au><au>Johnson, Cynthia R.</au><au>Butter, Eric M.</au><au>Lecavalier, Luc</au><au>Scahill, Lawrence</au><au>Aman, Michael G.</au><au>McDougle, Christopher J.</au><au>Arnold, L. Eugene</au><au>Swiezy, Naomi B.</au><au>Sukhodolsky, Denis G.</au><au>Mulick, James A.</au><au>White, Susan W.</au><au>Bearss, Karen</au><au>Hollway, Jill A.</au><au>Stigler, Kimberly A.</au><au>Dziura, James</au><au>Yu, Sunkyung</au><au>Sacco, Kelley</au><au>Vitiello, Benedetto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders</atitle><jtitle>Journal of developmental and physical disabilities</jtitle><stitle>J Dev Phys Disabil</stitle><addtitle>J Dev Phys Disabil</addtitle><date>2013-06-01</date><risdate>2013</risdate><volume>25</volume><issue>3</issue><spage>355</spage><epage>371</epage><pages>355-371</pages><issn>1056-263X</issn><eissn>1573-3580</eissn><abstract>A Structured Observational Analog Procedure (SOAP), an analogue measure of parent-child interactions, was used to assess treatment outcome in children with Autism Spectrum Disorder and serious behavior problems. It served as a secondary outcome measure in a 24-week, randomized trial of risperidone (MED;
N
= 49) versus risperidone plus parent training (COMB;
n
= 75) (ages 4–13 years). At 24-weeks, there was 28 % reduction in child inappropriate behavior during a Demand Condition (
p
= .0002) and 12 % increase in compliance to parental requests (
p
= .004) for the two treatment conditions combined. Parents displayed 64 % greater use of positive reinforcement (
p
= .001) and fewer repeated requests for compliance (
p
< .0001). In the analysis of covariance (ANCOVA), COMB parents used significantly more positive reinforcement (
p
= .01) and fewer restrictive statements (
p
< .05) than MED parents. The SOAP is sensitive to change in child and parent behavior as a function of risperidone alone and in combination with PMT and can serve as a valuable complement to parent and clinician-based measures.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>23730123</pmid><doi>10.1007/s10882-012-9316-y</doi><tpages>17</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Analysis of covariance Antipsychotics Autism Autism Spectrum Disorders Autistic children Behavior problems Behavioral Science and Psychology Behaviour disordered children Child and School Psychology Compliance Developmental disorders Inappropriateness Original Article Outcome Measures Outcomes of Treatment Parent Child Relationship Parent-child relations Parenthood education Parents & parenting Pediatrics Pervasive developmental disorders Positive reinforcement Psychology Public Health Reinforcement Risperidone Statistical Analysis |
title | Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders |
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