DILI: New Insights into Diagnosis and Management

Drug-induced liver injury continues to have a significant impact. With over 1000 drugs now registered as causing DILI, this form of liver injury is the most cited reason for withdrawal of a drug from the marketplace. Despite this, the diagnosis of DILI continues to rely on subjective measures and ex...

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Bibliographic Details
Published in:Current Hepatitis Reports 2013-03, Vol.12 (1), p.53-58
Main Authors: Tran, Thanh, Lee, William M.
Format: Article
Language:English
Subjects:
Complex Clinical Issues (SA Harrison and NS Reau
Hepatology
Medicine
Medicine & Public Health
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Summary:Drug-induced liver injury continues to have a significant impact. With over 1000 drugs now registered as causing DILI, this form of liver injury is the most cited reason for withdrawal of a drug from the marketplace. Despite this, the diagnosis of DILI continues to rely on subjective measures and expert opinion with results that are both difficult to verify and reproduce. However, recent developments in DILI research may provide new insights to improve diagnosis and treatment in the future.
ISSN:1540-3416
2195-9595
1541-0706
DOI:10.1007/s11901-012-0159-x