Dysregulated relationship of inflammation and oxidative stress in major depression

Highlight ► The relationship of inflammation to oxidation may be disturbed in untreated major depression; this may reflect or contribute to increased risk of co-morbid medical illnesses.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2013-07, Vol.31, p.143-152
Main Authors: Rawdin, B.J, Mellon, S.H, Dhabhar, F.S, Epel, E.S, Puterman, E, Su, Y, Burke, H.M, Reus, V.I, Rosser, R, Hamilton, S.P, Nelson, J.C, Wolkowitz, O.M
Format: Article
Language:English
Subjects:
Adult
Allergy and Immunology
Antidepressive Agents - pharmacology
Antidepressive Agents - therapeutic use
Depression
Depressive Disorder, Major - drug therapy
Depressive Disorder, Major - metabolism
F2-isoprostane
Female
Humans
IL-10
IL-6
Inflammation
Inflammation - metabolism
Interleukin-10 - blood
Interleukin-6 - blood
Male
Middle Aged
Oxidation
Oxidative stress
Oxidative Stress - drug effects
Oxidative Stress - physiology
Psychiatry
Sertraline
Sertraline - pharmacology
Sertraline - therapeutic use
Treatment Outcome
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Description
Summary:Highlight ► The relationship of inflammation to oxidation may be disturbed in untreated major depression; this may reflect or contribute to increased risk of co-morbid medical illnesses.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2012.11.011