A case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma

We report on a case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. A 70-year-old man was admitted to our hospital with fatigue, myalgia and an elevated creatine phosphokinase level. He was diagnosed as rhabdomyolysis related to sorafenib treatment for advance...

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Bibliographic Details
Published in:Clinical journal of gastroenterology 2013-06, Vol.6 (3), p.255-257
Main Authors: Tsuji, Kunihiro, Takemura, Kenichi, Minami, Keisuke, Teramoto, Ryota, Nakashima, Keisuke, Yamada, Shinya, Doyama, Hisashi, Oiwake, Hisanori, Hasatani, Kenkou
Format: Article
Language:English
Subjects:
Abdominal Surgery
Case Report
Colorectal Surgery
Gastroenterology
Hepatology
Medicine
Medicine & Public Health
Surgical Oncology
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Summary:We report on a case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. A 70-year-old man was admitted to our hospital with fatigue, myalgia and an elevated creatine phosphokinase level. He was diagnosed as rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. After discontinuation of sorafenib, his fatigue and myalgia resolved and his creatine phosphokinase level returned to normal. Rhabdomyolysis related to sorafenib treatment is rare adverse effect. This is the first detailed case report of rhabdomyolysis related to sorafenib treatment.
ISSN:1865-7257
1865-7265
DOI:10.1007/s12328-013-0381-2