The Association of Mental Health over Time with Cardiac Outcomes in HEMO Study Patients

Poor mental health over time is significantly associated with cardiovascular morbidity and mortality in the general population, which is the leading cause of death in dialysis patients. Most studies of dialysis patients, however, have investigated the relationship between baseline mental health meas...

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Bibliographic Details
Published in:Clinical journal of the American Society of Nephrology 2012-06, Vol.7 (6), p.957-964
Main Authors: Kang, Ea Wha, Pike, Francis, Ramer, Sarah, Abdel-Kader, Khaled, Myaskovsky, Larissa, Dew, Mary Amanda, Unruh, Mark
Format: Article
Language:English
Subjects:
Adult
Aged
Cause of Death
Female
Heart Diseases - mortality
Heart Diseases - psychology
Hospitalization
Humans
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - psychology
Kidney Failure, Chronic - therapy
Logistic Models
Male
Mental Health
Middle Aged
Multivariate Analysis
Original
Prevalence
Proportional Hazards Models
Prospective Studies
Renal Dialysis - adverse effects
Renal Dialysis - mortality
Risk Assessment
Risk Factors
Surveys and Questionnaires
Survival Analysis
Time Factors
Treatment Outcome
United States
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Summary:Poor mental health over time is significantly associated with cardiovascular morbidity and mortality in the general population, which is the leading cause of death in dialysis patients. Most studies of dialysis patients, however, have investigated the relationship between baseline mental health measurements and all-cause mortality and not mental health measured longitudinally throughout a study and cause-specific mortality. This study examined the association of changes in mental health over time with all-cause and cause-specific deaths and cardiac hospitalizations in the Hemodialysis study patients. Mental health was assessed at baseline and annually during the study with short form 36 mental health index scores. Poorer mental health was defined by a mental health index score≤60. Patients with poorer mental health at baseline were more likely to have less than a high school education and be unmarried, have significantly higher index of coexistent disease scores, and report taking β-blockers and sleep medications. Low mental health scores over time were independently associated with a decrease in survival time from all-cause mortality by -0.06 (-0.10, -0.03; P
ISSN:1555-9041
1555-905X
DOI:10.2215/CJN.06730711