The relationship between training status, blood pressure and uric acid in adults and elderly

Hypertension can be generated by a great number of mechanisms including elevated uric acid (UA) that contribute to the anion superoxide production. However, physical exercise is recommended to prevent and/or control high blood pressure (BP). The purpose of this study was to investigate the relations...

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Bibliographic Details
Published in:BMC cardiovascular disorders 2013-06, Vol.13 (1), p.44-44, Article 44
Main Authors: Trapé, Atila Alexandre, Jacomini, André Mourão, Muniz, Jaqueline Jóice, Sertorio, Jonas Tadeu Cau, Tanus-Santos, José Eduardo, do Amaral, Sandra Lia, Zago, Anderson Saranz
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Analysis
Batteries
Blood pressure
Blood Pressure - physiology
Cholesterol
Diet
Exercise
Exercise Test - methods
Female
Health aspects
Humans
Hypertension
Male
Measurement
Middle Aged
Nitric oxide
Oxidative Stress - physiology
Physical Endurance - physiology
Physical fitness
Physical Fitness - physiology
Uric acid
Uric Acid - blood
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Summary:Hypertension can be generated by a great number of mechanisms including elevated uric acid (UA) that contribute to the anion superoxide production. However, physical exercise is recommended to prevent and/or control high blood pressure (BP). The purpose of this study was to investigate the relationship between BP and UA and whether this relationship may be mediated by the functional fitness index. All participants (n = 123) performed the following tests: indirect maximal oxygen uptake (VO2max), AAHPERD Functional Fitness Battery Test to determine the general fitness functional index (GFFI), systolic and diastolic blood pressure (SBP and DBP), body mass index (BMI) and blood sample collection to evaluate the total-cholesterol (CHOL), LDL-cholesterol (LDL-c), HDL-cholesterol (HDL-c), triglycerides (TG), uric acid (UA), nitrite (NO2) and thiobarbituric acid reactive substances (T-BARS). After the physical, hemodynamic and metabolic evaluations, all participants were allocated into three groups according to their GFFI: G1 (regular), G2 (good) and G3 (very good). Baseline blood pressure was higher in G1 when compared to G3 (+12% and +11%, for SBP and DBP, respectively, p
ISSN:1471-2261
1471-2261
DOI:10.1186/1471-2261-13-44