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Estimating energy expenditure in mice using an energy balance technique

Objective: To compare, in mice, the accuracy of estimates of energy expenditure (EE) using an energy balance technique (TEE bal : food energy intake and body composition change) vs indirect calorimetry (TEE IC ). Subjects: In 32 male C57BL/6J mice, EE was estimated using an energy balance (caloric i...

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Bibliographic Details
Published in:International Journal of Obesity 2013-03, Vol.37 (3), p.399-403
Main Authors: Ravussin, Y, Gutman, R, LeDuc, C A, Leibel, R L
Format: Article
Language:English
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Summary:Objective: To compare, in mice, the accuracy of estimates of energy expenditure (EE) using an energy balance technique (TEE bal : food energy intake and body composition change) vs indirect calorimetry (TEE IC ). Subjects: In 32 male C57BL/6J mice, EE was estimated using an energy balance (caloric intake minus change in body energy stores) method over a 37-day period. EE was also measured in the same animals by indirect calorimetry. These measures were compared. Results: The two methods were highly correlated ( r 2 =0.87: TEE bal =1.07*TEE IC –0.22, P
ISSN:0307-0565
1476-5497
DOI:10.1038/ijo.2012.105