Corticosteroid Induced, HHV-8 Positive Kaposi’s Sarcoma in a Non-HIV Elderly Patient

Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Oth...

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Bibliographic Details
Published in:Journal of the Islamic Medical Association of North America 2012-08, Vol.44 (1)
Main Authors: Wani, Gh Mohiuddin, Ahmad, Sheikh Manzoor, Qayoom, Seema, Khursheed, Bilquees, Khan, A.R.
Format: Article
Language:English
Subjects:
Case Report
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Summary:Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.
ISSN:0899-8299
2160-9829
DOI:10.5915/44-1-9317