Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physio...

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Bibliographic Details
Published in:International journal of molecular sciences 2007-07, Vol.8 (7), p.606-617
Main Authors: Huang, Jun, Huang, Qing-Dong, Zhang, Ji, Zhou, Li-Hong, Li, Qiang-Lin, Li, Kun, Jiang, Ning, Lin, Hong-Hui, Wu, Jiang, Yu, Xiao-Qi
Format: Article
Language:English
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Full Research Paper
Ligands
Nanoparticles
Polyamines
Zinc
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Summary:Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physiological conditions.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/i8070606