Crohn's disease complicated by intestinal infection with methicillin-resistant Staphylococcus aureus

We report on a 24-year-old male patient with history of bloody diarrhea, abdominal pain and vomiting. Endoscopy revealed massive ulcerative discontinuous proctosigmoiditis with deep, sharply demarcated epithelial denudations and enterotoxigenic methicillin-resistant Staphylococcus aureus (MRSA) was...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2013-07, Vol.19 (27), p.4418-4421
Main Authors: Bettenworth, Dominik, Nowacki, Tobias M, Friedrich, Alexander, Becker, Karsten, Wessling, Johannes, Heidemann, Jan
Format: Article
Language:English
Subjects:
Adult
Anti-Infective Agents - therapeutic use
Case Report
Colitis - microbiology
Colitis - pathology
Crohn Disease - complications
Crohn Disease - microbiology
Cross Infection - complications
Cross Infection - microbiology
Endoscopy
Humans
Inflammation - microbiology
Inflammation - pathology
Intestines - microbiology
Intestines - pathology
Male
Methicillin-Resistant Staphylococcus aureus
Staphylococcal Infections - complications
Staphylococcal Infections - microbiology
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Summary:We report on a 24-year-old male patient with history of bloody diarrhea, abdominal pain and vomiting. Endoscopy revealed massive ulcerative discontinuous proctosigmoiditis with deep, sharply demarcated epithelial denudations and enterotoxigenic methicillin-resistant Staphylococcus aureus (MRSA) was detected in mucosal biopsies. After treatment with linezolide and steroids, a significant amelioration of colitis was detected and testing for MRSA became negative. In face of the case presented here, we suggest that in patients with refractory inflammatory bowel disease (IBD), microbiological assessment should be performed to detect a possible Staphylococcus aureus infection in order to initiate an antimicrobial treatment in addition to IBD-specific treatment.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v19.i27.4418