Oral Liquid l-Thyroxine (l-T4) May Be Better Absorbed Compared to l-T4 Tablets Following Bariatric Surgery

Drug malabsorption is a potential concern after bariatric surgery. We present four case reports of hypothyroid patients who were well replaced with thyroxine tablets to euthyroid thyrotropin (TSH) levels prior to Roux-en-Y gastric bypass surgery. These patients developed elevated TSH levels after th...

Full description

Saved in:
Bibliographic Details
Published in:Obesity surgery 2013-09, Vol.23 (9), p.1493-1496
Main Authors: Pirola, Ilenia, Formenti, Anna M., Gandossi, Elena, Mittempergher, Francesco, Casella, Claudio, Agosti, Barbara, Cappelli, Carlo
Format: Article
Language:English
Subjects:
Adult
Brief Communication
Drug therapy
Female
Gastric Bypass - adverse effects
Gastrointestinal surgery
Humans
Hypothyroidism
Malabsorption Syndromes - drug therapy
Medicine
Medicine & Public Health
Middle Aged
Obesity
Obesity, Morbid - drug therapy
Obesity, Morbid - metabolism
Obesity, Morbid - surgery
Surgery
Suspensions
Tablets
Therapeutic Equivalency
Thyrotropin - pharmacokinetics
Thyroxine - pharmacokinetics
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Drug malabsorption is a potential concern after bariatric surgery. We present four case reports of hypothyroid patients who were well replaced with thyroxine tablets to euthyroid thyrotropin (TSH) levels prior to Roux-en-Y gastric bypass surgery. These patients developed elevated TSH levels after the surgery, the TSH responded reversibly to switching from treatment with oral tablets to a liquid formulation.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-013-1015-y