Evaluation of safety and efficacy of radiation-sterilized bone allografts in reconstructive oral surgery

Bone grafting allows reconstruction of the atrophied or destroyed alveolar process. In orthopaedics and traumatology allogeneic grafting has been used to restore defects of osseous tissue for over 60 years. In order to improve safety of the graft recipient, sterilized allogeneic grafts have been use...

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Bibliographic Details
Published in:Cell and tissue banking 2013-09, Vol.14 (3), p.367-374
Main Authors: Krasny, Marta, Krasny, Kornel, Kamiński, Artur, Zadurska, Małgorzata, Piekarczyk, Piotr, Fiedor, Piotr
Format: Article
Language:English
Subjects:
Adult
Aged
Allografts
Allografts - radiation effects
Alveolar Process - diagnostic imaging
Alveolar Process - surgery
Biomedical and Life Sciences
Biomedicine
Biotechnology
Bone Transplantation - adverse effects
Cell Biology
Female
Follow-Up Studies
Humans
Life Sciences
Male
Maxillofacial surgery
Middle Aged
Oral Surgical Procedures - adverse effects
Original Paper
Orthopedics
Radiation
Radiography
Reconstructive Surgical Procedures - adverse effects
Sterilization - methods
Transplant Surgery
Transplants & implants
Young Adult
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Summary:Bone grafting allows reconstruction of the atrophied or destroyed alveolar process. In orthopaedics and traumatology allogeneic grafting has been used to restore defects of osseous tissue for over 60 years. In order to improve safety of the graft recipient, sterilized allogeneic grafts have been use. The aim of the study was to assess the direct and long-term outcomes following augmentation of atrophied alveolar processes with the use of radiation-sterilized allogeneic bone grafts. Sixty-eight patients were surgically treated between 2004 and 2011: 29 underwent open sinus floor elevation, post-extraction alveoli augmentation was performed in 16 subjects and 23 underwent reconstruction of the atrophied alveolar process. Augmentation of bone defects used bone granulate in 63 patients and bone blocks stabilized with titanium screws in 5 patients. PRF membranes collected from the patient’s blood were also used in all the procedures. In each of the cases optimal dimensions of the alveolar process were obtained allowing embedment of BIOMET 3I dental implant/-s. In all the patients the defects were successfully restored with implant-supported prostheses. Radiation-sterilized allogeneic bone grafts proved to be safe and effective for the patients and manageable for the surgeon constituting a good alternative to autogeneic material.
ISSN:1389-9333
1573-6814
DOI:10.1007/s10561-012-9348-7