The Prevalence of Hepatitis C Virus Infection in Oral Lichen Planus in an Ethnic Chinese Cohort of 232 Patients

Aim Oral lichen planush （OLP） is a chronic inflammatory disease, and has been reported to have a correlation with hepatitis Cvirus （HCV） infection in some regional investigations. In this study, we investigated the prevalence of HCV in patients with oral lichen planus in an ethnic Chinese cohort. Me...

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Bibliographic Details
Published in:International journal of oral science 2010-06, Vol.2 (2), p.90-97
Main Authors: Zhou, Yu, Jiang, Lu, Liu, Jie, Zeng, Xin, Chen, Qian‐ming
Format: Article
Language:English
Subjects:
Adolescent
Adult
Asian Continental Ancestry Group
Chi-Square Distribution
China
Chronic Disease
Dentistry
Female
Hepacivirus - pathogenicity
Hepatitis C Antibodies - blood
Humans
Lichen Planus, Oral - blood
Lichen Planus, Oral - virology
Male
Medicine
Middle Aged
Oral and Maxillofacial Surgery
Original Scientific
original-scientific-article
Orthopedics
Socioeconomic Factors
Statistics, Nonparametric
Surgical Orthopedics
Surveys and Questionnaires
Young Adult
口服地衣
口腔卫生
慢性炎症性疾病
治疗方法
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Summary:Aim Oral lichen planush （OLP） is a chronic inflammatory disease, and has been reported to have a correlation with hepatitis Cvirus （HCV） infection in some regional investigations. In this study, we investigated the prevalence of HCV in patients with oral lichen planus in an ethnic Chinese cohort. Methodology The antibody of HCV infection was detected by using enzymelinked immunosorbent assay. Moreover, the clinical characteristics of whole the cohort have also been studied, such as the gender, age, clinical type, habits and social factors. Results Of all 232 patients, the antibody of HCV infection was detected positive in 4 patients （1.72%） using enzyme-linked immunosorbent assay. It was lower than that in control group of 2.5%, but not significant （P=0.309）. The positive rate of HCV antibody in the erosive type ones （4.2%） was higher than that in the reticular type ones （1.0%）, but this difference was proved to be not significant （P=0.389）. The clinical characteristics of whole cohort, such as the gender, age, clinical type, habits and social factors, showed the outcome obtained in the present study were similar to thao of our previous study. Conclusion HCV may play no etiological role in oral lichen planus in ethnic Chinese OLP patients.
ISSN:1674-2818
2049-3169
DOI:10.4248/IJOS10028