Correlation between anxiety-depression status and cytokines in diarrhea-predominant irritable bowel syndrome

The aim of this study was to investigate the correlation between anxiety-depression status and cytokines in diarrhea-predominant irritable bowel syndrome (IBS-D). IBS-D patients were divided into an anxiety-depression IBS-D group and a non-anxiety-depression IBS-D group. Patients without IBS, anxiet...

Full description

Saved in:
Bibliographic Details
Published in:Experimental and therapeutic medicine 2013-07, Vol.6 (1), p.93-96
Main Author: GAO, JINGGUO
Format: Article
Language:English
Subjects:
Abdomen
Antigens
Anxiety
Colon
cytokine
Cytokines
depression
Diarrhea
Hospitals
IL-10
IL-1β
Immune system
Irritable bowel syndrome
Membranes
Pain
Smooth muscle
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of this study was to investigate the correlation between anxiety-depression status and cytokines in diarrhea-predominant irritable bowel syndrome (IBS-D). IBS-D patients were divided into an anxiety-depression IBS-D group and a non-anxiety-depression IBS-D group. Patients without IBS, anxiety or depression were selected as the control group. Scoring was performed using the self-rating anxiety scale (SAS) and self-rating depression scale (SDS). Levels of IL-1β and IL-10 in the blood and sigmoid colon mucosa were detected, and the proportions of IL-1β- and IL-10-positive cells in the sigmoid colon mucosa were determined. The results demonstrated that the SDS and SAS scores in the IBS-D group were significantly higher than those in the control group (P
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2013.1101