Severe eyelid oedema in Graves’ ophthalmopathy

We report a case of severe eyelid oedema due to Graves’ ophthalmopathy (GO). The aim was to present a case report and review of the literature about eyelid oedema due to GO. The case report includes a history of patient data and literature review. The patient was offered intravenous methylprednisolo...

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Bibliographic Details
Published in:BMJ case reports 2013-07, Vol.2013, p.bcr2013010305
Main Authors: Anagnostis, Panagiotis, Adamidou, Fotini, Poulasouchidou, Maria, Karras, Spyridon
Format: Article
Language:English
Subjects:
Edema - drug therapy
Edema - etiology
Europe (West)
Eyelid Diseases - drug therapy
Eyelid Diseases - etiology
Female
Glucocorticoids - therapeutic use
Graves Ophthalmopathy - complications
Graves Ophthalmopathy - drug therapy
Humans
Methylprednisolone - therapeutic use
Middle Aged
Radiation therapy
Severity of Illness Index
Thyroid gland
Unusual Presentation of More Common Disease/Injury
White
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Summary:We report a case of severe eyelid oedema due to Graves’ ophthalmopathy (GO). The aim was to present a case report and review of the literature about eyelid oedema due to GO. The case report includes a history of patient data and literature review. The patient was offered intravenous methylprednisolone and gave consent. A dosage of 500 mg intravenous methylprednisolone once weekly for 6 weeks, followed by 250 mg intravenous methylprednisolone once weekly for 6 weeks, with a total treatment period of 12 weeks was given. Up to day, minor improvement has been observed. Severe eyelid oedema due to GO is a rare manifestation of Graves’ disease. In cases of active and moderate-to-severe disease, treatment with intravenous glucorticoids is recommended alone or with orbital radiotherapy, followed by rehabilitative surgery.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2013-010305