Towards a Casa Segura: a consumer product study of the effect of insecticide-treated curtains on Aedes aegypti and dengue virus infections in the home

The home, or domicile, is the principal environment for transmission of dengue virus (DENV) between humans and mosquito vectors. Community-wide distribution of insecticide-treated curtains (ITCs), mimicking vector control program-driven interventions, has shown promise to reduce DENV infections. We...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2013-08, Vol.89 (2), p.385-397
Main Authors: Loroño-Pino, María Alba, García-Rejón, Julián E, Machain-Williams, Carlos, Gomez-Carro, Salvador, Nuñez-Ayala, Guadalupe, Nájera-Vázquez, Maria del Rosario, Losoya, Arturo, Aguilar, Lyla, Saavedra-Rodriguez, Karla, Lozano-Fuentes, Saul, Beaty, Meaghan K, Black, 4th, William C, Keefe, Thomas J, Eisen, Lars, Beaty, Barry J
Format: Article
Language:English
Subjects:
Aedes - drug effects
Aedes - genetics
Aedes - virology
Aedes aegypti
Animals
Dengue - epidemiology
Dengue - prevention & control
Dengue virus
Dengue Virus - physiology
Female
Housing
Insect Vectors - drug effects
Insect Vectors - genetics
Insect Vectors - virology
Insecticide Resistance - genetics
Insecticides - chemistry
Insecticides - pharmacology
Mexico - epidemiology
Mosquito Control - methods
Nitriles - chemistry
Nitriles - pharmacology
Pyrethrins - chemistry
Pyrethrins - pharmacology
Textiles
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Summary:The home, or domicile, is the principal environment for transmission of dengue virus (DENV) between humans and mosquito vectors. Community-wide distribution of insecticide-treated curtains (ITCs), mimicking vector control program-driven interventions, has shown promise to reduce DENV infections. We conducted a Casa Segura consumer product intervention study in Mérida, Mexico to determine the potential to reduce intradomicillary DENV transmission through ITC use in individual homes. Dengue virus infections in mosquitoes and in humans were reduced in homes with ITCs in one of two study subareas. Overall, ITCs reduced intradomicillary DENV transmission; ITC homes were significantly less likely to experience multiple DENV infections in humans than NTC homes. Dengue virus-infected Aedes aegypti females were reduced within the ITC homes where curtain use was highest. Some homes yielded up to nine infected Ae. aegypti females. This study provides insights regarding best practices for Casa Segura interventions to protect homes from intradomicillary DENV transmission.
ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.12-0772