Serum cystatin C is a poor biomarker for diagnosing acute kidney injury in critically-ill children

Background: Accurate diagnosis of acute kidney injury (AKI) is problematic especially in critically-ill patients in whom renal function is in an unsteady state. Aim: Our aim was to evaluate the role of serum (S.) cystatin C as an early biomarker of AKI in critically-ill children. Subjects and Method...

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Bibliographic Details
Published in:Indian journal of critical care medicine 2013-03, Vol.17 (2), p.92-98
Main Authors: Hamed, Hanan, El-Sherbini, Seham, Barakat, Nahla, Farid, Tarek, Rasheed, Enas
Format: Article
Language:English
Subjects:
Acute renal failure
Biomarkers
Care and treatment
Children
Critically ill
Diagnosis
Drug dosages
Enzymes
Injuries
Intensive care
Molecular weight
Mortality
Prevention
Proteins
Rodents
Ventilation
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Summary:Background: Accurate diagnosis of acute kidney injury (AKI) is problematic especially in critically-ill patients in whom renal function is in an unsteady state. Aim: Our aim was to evaluate the role of serum (S.) cystatin C as an early biomarker of AKI in critically-ill children. Subjects and Methods: S. creatinine and S. cystatin C were measured in 32 critically-ill children who were at risk for developing AKI. AKI was defined by both: Risk,-injury,-failure,-loss, and-endstage renal disease (RIFLE) classification and glomerular filtration rate (GFR)
ISSN:0972-5229
1998-359X
DOI:10.4103/0972-5229.114829