Resistance of Human Cytomegalovirus to Cyclopropavir Maps to a Base Pair Deletion in the Open Reading Frame of UL97

• Published in: Antimicrobial Agents and Chemotherapy 2013-09, Vol.57 (9), p.4343-4348
• Main Authors: GENTRY, Brian G, VOLLMER, Laura E, HALL, Ellie D, BORYSKO, Katherine Z, ZEMLICKA, Jiri, KAMIL, Jeremy P, DRACH, John C
• Format: Article
• Language: English
• Subjects: Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - pharmacology; Base pairs; Base Sequence; Biological and medical sciences; Cells, Cultured; Cyclopropanes - pharmacology; Cytomegalovirus; Cytomegalovirus - drug effects; Cytomegalovirus - genetics; Cytomegalovirus - growth & development; Drug Resistance, Viral - drug effects; Drug Resistance, Viral - genetics; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - virology; Frameshift Mutation; Ganciclovir - pharmacology; Guanine - analogs & derivatives; Guanine - pharmacology; Human cytomegalovirus; Humans; Medical sciences; Molecular Sequence Data; Open Reading Frames; Pharmacology. Drug treatments; Protein Kinase Inhibitors - pharmacology; Protein Kinases; Protein Kinases - genetics; Protein Kinases - metabolism; Viral Proteins; Viral Proteins - genetics; Viral Proteins - metabolism
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00214-13

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