New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives

Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step...

Full description

Saved in:
Bibliographic Details
Published in:ISRN Organic Chemistry 2012-07, Vol.2012, p.1-4
Main Authors: Shchepina, Nadezhda E., Avrorin, Viktor V., Badun, Gennady A., Lewis, Scott B., Shurov, Sergey N.
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step synthesis of tritium-labeled N-phenyl-2-phenylquinolinium salt—lipophilic radioactive biological marker has been elaborated.
ISSN:2090-5157
2090-5149
2090-5157
DOI:10.5402/2012/526867