Copper Perchlorate Hexahydrate : An Efficient Catalyst for the Green Synthesis of Polyhydroquinolines under Ultrasonication

Copper perchlorate hexahydrate as an efficient catalyst was used for the synthesis of polyhydroquinolines by four-component condensation reaction of aldehyde, ethyl acetoacetate, dimedone, and ammonium acetate in excellent yields and short reaction times at room temperature under ultrasound irradiat...

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Bibliographic Details
Published in:ISRN Organic Chemistry 2011, Vol.2011 (2011), p.1-4
Main Authors: Kaur, Balbir, Puri, Saurabh, Parmar, Anupama, Kumar, Harish
Format: Article
Language:English
Subjects:
Acids
Efficiency
Green chemistry
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Summary:Copper perchlorate hexahydrate as an efficient catalyst was used for the synthesis of polyhydroquinolines by four-component condensation reaction of aldehyde, ethyl acetoacetate, dimedone, and ammonium acetate in excellent yields and short reaction times at room temperature under ultrasound irradiation. This novel synthetic method is especially favoured because it provides a synergy between copper perchlorate hexahydrate and ultrasound irradiation which offers the advantages of high yields, short reaction times, simplicity, and easy workup compared to the conventional methods reported in the literature.
ISSN:2090-5149
2090-5157
DOI:10.5402/2011/948685