Role of stereotactic biopsy in histological diagnosis of multiple brain lesions

Background and Aim : The current advances in diagnostic and therapeutic modalities and increasing in survival of patients with systemic diseases and immunosuppressive cases have caused to increasing frequency and variety of Central Nervous System neuropathologic processes indicating the necessary ne...

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Bibliographic Details
Published in:Asian journal of neurosurgery 2013-04, Vol.8 (2), p.69-73
Main Authors: Meshkini, Ali, Shahzadi, Sohrab, Alikhah, Hossein, Naghavi-Behzad, Mohammad
Format: Article
Language:English
Subjects:
Abnormalities
Biopsy
Brain
Histology
Methods
Original
ORIGINAL ARTICLE
Stereotaxic techniques
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Summary:Background and Aim : The current advances in diagnostic and therapeutic modalities and increasing in survival of patients with systemic diseases and immunosuppressive cases have caused to increasing frequency and variety of Central Nervous System neuropathologic processes indicating the necessary need for accurate localization of space-occupying lesions by cytology and histology. This study was aimed to evaluate the usefulness and safety of stereotactic biopsy in histological diagnosis of such lesions. Materials and Methods: Of 2081 patients underwent stereotactic biopsy of brain lesions using Riechert-Mundinger system, 158 had multifocal brain lesions, and were enrolled. Results: The ages of studied cases were ranged from 2 years to 75 years (Mean age: 41.3 year), 114 were male and 44 were females. Incidence of histopathologic diagnosis of multifocal brain lesions included Astrocytoma grade II (41.3%), Astrocytoma grade I (12.9%), glioblastoma multiform (11.1%), Astrocytoma grade III (10.2%), malignant lymphoma (10.2%), metastasis (4.6%), pilocytic Astrocytoma (2.7%), abscess (2.7%), craniopharyngioma (1.8%) vascular malformations (0.9%), and tuberculosis (0.9%). Mortality due to operation is none. Conclusions : Histopathologic diagnosis of multiple brain lesions is necessary for decision of appropriate management and stereotactic biopsy of brain lesion is a useful and safe method for histological diagnosis.
ISSN:1793-5482
2248-9614
DOI:10.4103/1793-5482.116374