Plasma extracellular vesicle protein content for diagnosis and prognosis of global cardiovascular disease

Cardiovascular disease is a major public health problem worldwide. Its growing burden is particularly ominous in Asia, due to increasing rates of major risk factors such as diabetes, obesity and smoking. There is an urgent need for early identification and treatment of individuals at risk of adverse...

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Bibliographic Details
Published in:Netherlands heart journal 2013-10, Vol.21 (10), p.467-471
Main Authors: Wang, J. W., Gijsberts, C. M., Seneviratna, A., de Hoog, V. C., Vrijenhoek, J. E. P., Schoneveld, A. H., Chan, M. Y., Lam, C. S. P., Richards, A. M., Lee, C. N., Mosterd, A., Sze, S. K., Timmers, L., Lim, S. K., Pasterkamp, G., de Kleijn, D. P. V.
Format: Article
Language:English
Subjects:
Cardiology
ICIN
Medical Education
Medicine
Medicine & Public Health
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Summary:Cardiovascular disease is a major public health problem worldwide. Its growing burden is particularly ominous in Asia, due to increasing rates of major risk factors such as diabetes, obesity and smoking. There is an urgent need for early identification and treatment of individuals at risk of adverse cardiovascular events. Plasma extracellular vesicle proteins are novel biomarkers that have been shown to be useful in the diagnosis, risk stratification and prognostication of patients with cardiovascular disease. Ongoing parallel biobank initiatives in European (the Netherlands) and Asian (Singapore) populations offer a unique opportunity to validate these biomarkers in diverse ethnic groups.
ISSN:1568-5888
1876-6250
DOI:10.1007/s12471-013-0462-3