A new prospect in cancer therapy： targeting cancer stem cells to eradicate cancer

According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent bre...

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Bibliographic Details
Published in:Ai zheng 2012-12, Vol.31 (12), p.564-572
Main Authors: Chen, Li-Sha, Wang, An-Xin, Dong, Bing, Pu, Ke-Feng, Yuan, Li-Hua, Zhu, Yi-Min
Format: Article
Language:English
Subjects:
Antineoplastic Agents - pharmacology
Antineoplastic Agents - therapeutic use
Biomarkers, Tumor - metabolism
Cell Differentiation - drug effects
Drug Carriers
Gold - administration & dosage
Humans
Nanostructures
Neoplasms - drug therapy
Neoplasms - metabolism
Neoplasms - pathology
Neoplastic Stem Cells - drug effects
Neoplastic Stem Cells - metabolism
Neoplastic Stem Cells - pathology
Review
根除
癌症
肿瘤干细胞
肿瘤治疗
靶向制剂
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Summary:According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research.
ISSN:1000-467X
1944-446X
DOI:10.5732/cjc.011.10444