Childhood socioeconomic status, telomere length, and susceptibility to upper respiratory infection

Highlight • Lower childhood SES is related to shorter CD8+ CD28− telomere length and poorer resistance to the common cold, with telomere length partly mediating the SES-cold association.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2013-11, Vol.34, p.31-38
Main Authors: Cohen, Sheldon, Janicki-Deverts, Denise, Turner, Ronald B, Marsland, Anna L, Casselbrant, Margaretha L, Li-Korotky, Ha-Sheng, Epel, Elissa S, Doyle, William J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Allergy and Immunology
CD28 Antigens - immunology
CD8 Antigens - immunology
CD8+CD28
Childhood socioeconomic status
Common cold
Common Cold - genetics
Disease Susceptibility
Female
Host resistance
Humans
Infection
Male
Middle Aged
Psychiatry
Respiratory Tract Infections - genetics
Rhinovirus
Rhinovirus - pathogenicity
Socioeconomic Factors
Socioeconomic status
T-Lymphocytes - immunology
T-Lymphocytes - ultrastructure
Telomere
Telomere Homeostasis
Telomere length
Upper respiratory infection
Viral-challenge
Young Adult
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Description
Summary:Highlight • Lower childhood SES is related to shorter CD8+ CD28− telomere length and poorer resistance to the common cold, with telomere length partly mediating the SES-cold association.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2013.06.009