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Uncertain inheritance transgenerational effects of environmental exposures

According to Chadwick, current hypotheses lean toward epigenetic inheritance patterns, which involve chemical modifications to the DNA rather than mutations of the DNA sequence itself. According to Roseboom, this finding suggests prenatal famine could lead to changes in gene expression via changes i...

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Bibliographic Details
Published in:Environmental health perspectives 2013-10, Vol.121 (10), p.A298-A303
Main Author: Schmidt, Charles W
Format: Article
Language:English
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Summary:According to Chadwick, current hypotheses lean toward epigenetic inheritance patterns, which involve chemical modifications to the DNA rather than mutations of the DNA sequence itself. According to Roseboom, this finding suggests prenatal famine could lead to changes in gene expression via changes in methylation.
ISSN:0091-6765
1552-9924
DOI:10.1289/ehp.121-a298