The relationship between acute and chronic hyperglycemia and outcomes in burn injury

A significant proportion of patients with burn injury have diabetes. Although hyperglycemia during critical illness has been associated with poor outcomes, patients with chronic hyperglycemia based on elevated hemoglobin A1c (HbA1c) measurements at admission have been shown to tolerate higher glucos...

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Bibliographic Details
Published in:Journal of burn care & research 2013-01, Vol.34 (1), p.109-114
Main Authors: Murphy, Claire V, Coffey, Rebecca, Wisler, Jon, Miller, Sidney F
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Burns - complications
Burns - physiopathology
Chi-Square Distribution
Chronic Disease
Endpoint Determination
Female
Glycated Hemoglobin A - analysis
Humans
Hyperglycemia - complications
Hyperglycemia - physiopathology
Male
Middle Aged
Retrospective Studies
Statistics, Nonparametric
Survival Rate
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Summary:A significant proportion of patients with burn injury have diabetes. Although hyperglycemia during critical illness has been associated with poor outcomes, patients with chronic hyperglycemia based on elevated hemoglobin A1c (HbA1c) measurements at admission have been shown to tolerate higher glucose levels during hospitalization. This relationship has not been evaluated in the burn population. The objective of this study was to examine the impact of chronic glucose control on outcomes in the acute period after burn. This is a retrospective analysis comparing outcomes in patients with chronic hyperglycemia (HbA1c ≥ 6.5%) and euglycemia (HbA1c
ISSN:1559-047X
1559-0488
DOI:10.1097/BCR.0b013e3182700025