Survival of >20 years in a myeloma patient with an unusual combination of t(14;16) and hyperdiploidy: A case report

The current case report presents the prolonged survival of >20 years in a myeloma patient with secondary plasma cell leukemia and myelomatous pleural effusion. FISH on marrow plasma cells showed hyperdiploidy and concomitant t(14;16) and karyotypes predicting superior and short survival. The poss...

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Bibliographic Details
Published in:Oncology letters 2013-12, Vol.6 (6), p.1663-1664
Main Authors: CHIM, CHOR SANG, MA, EDMOND SIU KWAN
Format: Article
Language:English
Subjects:
Bone marrow
Case reports
Chemotherapy
hyperdiploidy
Leukemia
Medical prognosis
Multiple myeloma
myeloma
Oncology
Plasma
survival
t(14
16)
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Summary:The current case report presents the prolonged survival of >20 years in a myeloma patient with secondary plasma cell leukemia and myelomatous pleural effusion. FISH on marrow plasma cells showed hyperdiploidy and concomitant t(14;16) and karyotypes predicting superior and short survival. The possibility of primary hyperdiploidy with t(14;16) as a secondary event has been discussed.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2013.1624