Cycle scheduling for in vitro fertilization with oral contraceptive pills versus oral estradiol valerate: a randomized, controlled trial

Both oral contraceptive pills (OCPs) and estradiol (E2) valerate have been used to schedule gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization (IVF) cycles and, consequently, laboratory activities. However, there are no studies comparing treatment outcomes directly between these...

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Bibliographic Details
Published in:Reproductive biology and endocrinology 2013-09, Vol.11 (1), p.96-96, Article 96
Main Authors: Hauzman, Erik E, Zapata, Azucena, Bermejo, Alfonso, Iglesias, Carlos, Pellicer, Antonio, Garcia-Velasco, Juan A
Format: Article
Language:English
Subjects:
Adult
Analysis
Comparative analysis
Contraceptive drugs
Contraceptives
Contraceptives, Oral, Hormonal - therapeutic use
Data entry
Estradiol
Estradiol - analogs & derivatives
Estradiol - therapeutic use
Female
Fertilization in Vitro - methods
Fertilization in vitro, Human
Gonadotropin
Gonadotropin-Releasing Hormone - antagonists & inhibitors
Humans
Menstrual Cycle - drug effects
Pregnancy
Pregnancy Rate
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Summary:Both oral contraceptive pills (OCPs) and estradiol (E2) valerate have been used to schedule gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization (IVF) cycles and, consequently, laboratory activities. However, there are no studies comparing treatment outcomes directly between these two pretreatment methods. This randomized controlled trial was aimed at finding differences in ongoing pregnancy rates between GnRH antagonist IVF cycles scheduled with OCPs or E2 valerate. Between January and May 2012, one hundred consecutive patients (nonobese, regularly cycling women 18-38 years with normal day 3 hormone levels and
ISSN:1477-7827
1477-7827
DOI:10.1186/1477-7827-11-96